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Reversal of IDO-mediated cancer immune suppression

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Reversal of IDO-mediated cancer immune suppression

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Overcoming Cancer's Immune Suppression: Targeting Kynurenine Depletion with Therapeutic Enzymes

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Dissolve Macro Orange

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Reversal of IDO-mediated cancer immune suppression

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PEG-Kynureninase mediates prolonged depletion of Kyn in the TME and reverses the modulatory effects of IDO1/TDO upregulation in the tumor microenvironment.

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