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The impact of colloids and nanoparticles on intestinal drug absorption

The impact of colloids and nanoparticles on intestinal drug absorption

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The impact of colloids and nanoparticles on intestinal drug absorption

Webinar

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This series offers a valuable chance to deepen your understanding of using in-vitro permeability and flux studies to evaluate other affects.

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Dissolve Macro Orange

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The impact of colloids and nanoparticles on intestinal drug absorption

Webinar

This series presents a valuable opportunity to enhance your understanding of the utilization of in-vitro permeability and flux studies for assessing the impact of nanoparticles and colloidal structures on intestinal drug absorption.

Featured speakers:

  • Dr. Kiyohiko Sugano, Professor at Ritsumeikan University
  • Dr. Na Li, Assistant Professor of Pharmaceutics at the University of Connecticut
  • Dr. Patrick D. Sinko, Researcher at Uppsala University, Department of Pharmacy, Molecular Pharmaceutics Group
  • Karl Box, Chief Scientific Officer at Pion UK

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Dissolve Macro Orange
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Understanding Drug Diffusion in Peptide Hydrogels
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Webinar: What the Flux? Part 1
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pKa Measurements in 18 Minutes The SiriusT3 Fast UV pKa Method
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Liquid Phase Exfoliation of Graphite to Graphene
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Absorption-Driven Formulation Development
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Evaluating the Impact of Hyaluronidase on Subcutaneous mAb Formulations Using the SCISSOR N3 Platform
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Predicting Bioequivalence During Generic Drug Formulation
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Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability
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Development and validation of PAMPA-BBB QSAR model to predict brain penetration potential of novel drug candidates
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Physicochemical selectivity of the BBB microenvironment governing passive diffusion--matching with a porcine brain lipid extract artificial membrane permeability model
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PAMPA – a drug absorption in vitro model. 5. Unstirred water layer in iso-pH mapping assays and pKa flux – optimized design (pOD-PAMPA)
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Food effect and beyond: Understanding complex in vivo interactions through biorelevant dissolution-permeation assays-Day-1
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The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
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Drug ionization and physicochemical profiling
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Absorption using the  PAMPA Approach (in Optimization in Drug Discovery: In Vitro Methods)
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Micro Intrinsic Dissolution Rate (IDR) System
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Improved prediction of food effect on oral drug absorption
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Advancing Oral Drug Development with In Vitro Dissolution and Absorption Tools
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miniDT Small Volume Dissolution Testing
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Demonstrating the Excipient Effect In Vitro for Subcutaneous Pre-Clinical Formulation Analysis
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De-Risking development: Guiding formulation strategy with macroflux to predict human outcomes of kinetisol processed etravirine
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Simulating prodrug biotransformation in vitro - Conserving enzymatic activity within the SCISSOR N3 platform
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Pion Analytical Services SCISSOR
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Advancing in vitro-in vivo relationships: Steps in establishing an in vitro response for GLP-1 receptor agonists
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The Pion DissoSpec QC Dissolution Monitoring System
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Long Acting Injectable Adapters, USP 2
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3 Benefits of Conducting Simultaneous Dissolution and Permeability Tests
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4 Benefits to Conducting Simultaneous Dissolution and Permeability Experiments in Drug Development
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Carbon Nanotube Application Test Data and Results
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Conserving biorelevant enzymatic activity during in vitro subcutaneous drug testing
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DissoPRO Software v3.6
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Webinar: LIVE DEMO! Taking in vitro Data to in vivo Prediction
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Advancements in hydrogel formats to model potential drug interactions occurring at the subcutaneous injection site
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Subcutaneous Injection Site Simulator Assay
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Advancements in hydrogel formats to model potential drug interactions occurring at the subcutaneous injection site
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Predictor Software
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Service agreement plans
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SiriusT3 Lite - A PhysChem Platform
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Predictive power and operational use of SCISSOR to streamline SC biologics drug development
Webinar
The impact of colloids and nanoparticles on intestinal drug absorption
Publication
Hydrogel formats to model potential drug interactions occurring at the subcutaneous injection site
Publication
Bioequivalence prediction with small-scale biphasic dissolution and simultaneous dissolution-permeation apparatus - An aripiprazole case study
Brochure
Micro DeBEE
Webinar
Demonstrating the excipient effect in vitro for subcutaneous pre-clinical formulation analysis
Whitepaper
Pion's BEE Brand Homogenizers - The Ultimate Research Tool
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Effects of drug-rich phase properties formed by liquid-liquid phase separation on the drug membrane permeability analyzed using μFLUX
Whitepaper
Exploring the value of flux measurements in drug formulation and development: Bioavailability beyond dissolution rate alone. ADDF
Webinar
Introduction to Pion's BEE brand high-pressure homogenizers
Poster
Predicting the Relative In Vivo performance of Nanoformed and Crystalline Bulk Piroxicam Solid Suspensions from In Vitro Flux Measurements
Application Notes
Revisiting 2nd derivative UV spectroscopy for real-time monitoring of structural changes and complexations of macromolecules
Application Notes
Real time monitoring the extent of plasmid-liposome complexation using 2nd derivative fiber-optic UV spectroscopy
Application Notes
Development and characterization of an in vitro method for investigating pharmacokinetic behavior of long-acting subcutaneously injected therapeutics
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Using NaOH and NaCl instead of KOH and KCl
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Introduction to log P and log D measurement using PionT3
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Measuring log P of samples that are hard to dissolve in water and octanol
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The Determination of Solubility - Pion CheqSol Explained
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The use of cosolvent pKa assays for poorly soluble compounds
Application Notes
Measurement of Extreme pKas
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Solubility and Supersaturation - A Brief Introduction
Video
Scissor N3 overview and demo
Application Notes
Human Collagen’s Role within Artificial Extracellular Matrices used for in vivo Analysis of Injectable Formulations
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Scissor as a platform for the analysis of non-protein subcutaneous formulations
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Understanding excipient effect in vitro using the Pion Scissor
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Considerations on the Controlled Release of Injectable Insulin Using Scissor
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Scissor App Note_ECM-XR validation, peptides, mAbs, small molecules
E-book
How to Achieve Efficient & Consistent Particle Size Reduction e-book
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Homogenization For Cannabis e-book
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Advantages of Pion BEE brand Homogenizers for the Pharmaceutical Industry e-book
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7 Key Factors to Consider When Choosing A Cell Lysis Method - e-book
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Control of Oral Bioavailability by Particle Sizes
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Method for preparing propofol emulsion for vascular injection
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Development of Injectable PEGylated Liposome Encapsulating Disulfiram for Colorectal Cancer Treatment
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Nanoparticle Formation
Brochure
DeBEE 4000
Webinar
Barriers and solutions for mimicking an in vivo extracellular environment with in vitro tools
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Creating consistency & predictability in cannabis-infused beverages - Vertosa and Pion Inc.
Poster
Surface dissolution imaging to investigate the influence of common ion effect on Papaverine hydrochloride
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MiniDeBEE
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Nano DeBEE
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DeBEE 2000
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Dissolution Test Equipment & Methods for Pharma
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PrepEngine Demo: Chinese Traditional Medicine Sample Prep | Goji Berries & Baikal Skullcap Root
Poster
Interplay between Ketoconazole Cocrystal Supersaturation and Trans-membrane Flux Behavior In Simulated Intestinal Fluids
Poster
Application of In Situ Potentiometric Sensors to Study Dissolution-Precipitation Behavior of Electrospray-Generated Loperamide Nanoparticles
Poster
Cyclodextrin-Based Orally Fast Dissolving Drug Delivery System of Aripiprazole and Its In Vitro Dissolution-Permeation Testing Using µFLUX
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