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In-situ pH change on a biphasic dissolution model in the presence of SIFs

In-situ pH change on a biphasic dissolution model in the presence of SIFs

Poster

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In-situ pH change on a biphasic dissolution model in the presence of SIFs

Poster

Purpose A “biphasic dissolution model” has recently been developed to mimic the absorption of drugs under changing (gastrointestinal) pH conditions. This has been further developed to include simulated intestinal fluids (SIF) to better understand their effect on the uptake of orally dosed pharmaceutical drugs.

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