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In-situ pH change on a biphasic dissolution model in the presence of SIFs

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In-situ pH change on a biphasic dissolution model in the presence of SIFs

Poster

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Purpose: Biphasic dissolution model and simulated intestinal fluids (SIF) uptake of orally dosed pharmaceutical drugs

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Dissolve Macro Orange

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In-situ pH change on a biphasic dissolution model in the presence of SIFs

Poster

Purpose A “biphasic dissolution model” has recently been developed to mimic the absorption of drugs under changing (gastrointestinal) pH conditions. This has been further developed to include simulated intestinal fluids (SIF) to better understand their effect on the uptake of orally dosed pharmaceutical drugs.

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