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Biorelevant dissolution - the quest for simple in-vitro experiments

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Biorelevant dissolution - the quest for simple in-vitro experiments

Poster

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Dissolve Macro Orange

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Biorelevant dissolution - the quest for simple in-vitro experiments

Poster

This poster describes experiments that model the dissolution of drugs under conditions of steadily increasing pH in the presence of t simulated intestinal fluid, a Biorelevant Medium (BM).

Poster

Dissolve Macro Orange
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Prediction of in situ Blood-Brain Barrier Permeability using BBB PAMPA Model
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Impact of Biorelevant Media on Apparent Solubility and Biopharmaceutical Classification of Poorly Soluble Compounds
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Monitoring Supersaturation State of Solid Dispersions of Low Solubility Compounds
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Comparison of Naproxen Release from Nano- and Microsuspensions with Its Dissolution from Untreated and Micronized Powder
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In Situ Monitoring of Supersaturation State for Solid Dispersions of Low Soluble Compounds
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Application of Skin PAMPA to Differentiate Between Topical Pharmaceutical Formulations of Ibuprofen
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Dissolution and Precipitation Monitoring of Crystalline Salts
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Assessment of Transdermal Penetration Enhancement by Topical Pharmaceutical Excipients Using Skin PAMPA Method
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Real Time Monitoring of Dissolution, Supersaturation and Precipitation Processes in Dynamically Changing Biorelevant Media
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Novel HT Method for Parallel Excipient/Vehicle Formulation Studies
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Using Skin PAMPA For Transdermal Patch Testing
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Degree and Extent of Supersaturation of Amorphous Pharmaceuticals and Their Flux through Lipophilic Membranes
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Using flux experiments through artificial lipophilic membranes for predicting food effect for BCS Class 2 Compounds
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Application of simultaneous dissolution-absorption apparatus for screening formulations before bioequivalence studies
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Biorelevant drug release of Metformin dosage forms using complementary in vitro tools
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Differentiating itraconazole formulations based on the flux through artificial lipophilic membranes
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Utilization of pH-Metric Titration
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Determination of Polymer Effectiveness
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Determination of pKa values and Solubility pH Profiles of Selected ß blockers
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Validation of titrimetric measurement of pKa, logP and solubility
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Measuring the solubility of salts of basic drugs
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The intrinsic solubility of indomethacin
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A low volume method for screening Plasdone polymers
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