AAPS Advanced imaging, detection and prediction of initial gel formation and swelling of hypromellose compacts

The purpose of this work was to combine the Alicona® infinite focus microscope (IFM) with the new surface dissolution imaging system (SDi2) to detect similariDes or potenDal differences in the iniDal gel formaDon of HPMC CR and DC2 (K100M grades) pure polymer compacts.