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Low Volume Dissolution Assays

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Low Volume Dissolution Assays

Poster

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Dissolve Macro Orange

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Low Volume Dissolution Assays

Poster

Purpose This poster describes recent work within the European funded OrBiTo project on the dissolution behaviour of BCS Class II (poorly soluble) compounds using disk and powder methods and the impact of different media on the dissolution performance.

Poster

Dissolve Macro Orange
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Application of In Situ Potentiometric Sensors to Study Dissolution-Precipitation Behavior of Electrospray-Generated Loperamide Nanoparticles
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Cyclodextrin-Based Orally Fast Dissolving Drug Delivery System of Aripiprazole and Its In Vitro Dissolution-Permeation Testing Using µFLUX
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Dissolution, Free Drug Concentration and Permeability of Crystalline Nanoparticle Formulation Study Using In Situ Fiber Optic and Potentiometric Techniques
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Comparison of Miniaturized Intrinsic Dissolution Rate Measurement to Traditional Wood’s Apparatus
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Prediction of in situ Blood-Brain Barrier Permeability using BBB PAMPA Model
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Impact of Biorelevant Media on Apparent Solubility and Biopharmaceutical Classification of Poorly Soluble Compounds
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Monitoring Supersaturation State of Solid Dispersions of Low Solubility Compounds
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Comparison of Naproxen Release from Nano- and Microsuspensions with Its Dissolution from Untreated and Micronized Powder
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In Situ Monitoring of Supersaturation State for Solid Dispersions of Low Soluble Compounds
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Application of Skin PAMPA to Differentiate Between Topical Pharmaceutical Formulations of Ibuprofen
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Dissolution and Precipitation Monitoring of Crystalline Salts
Poster
Assessment of Transdermal Penetration Enhancement by Topical Pharmaceutical Excipients Using Skin PAMPA Method
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Universal Potentiometric Sensors: Application for Real Time Concentration Monitoring in Complex Biorelevant Media
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Real Time Monitoring of Dissolution, Supersaturation and Precipitation Processes in Dynamically Changing Biorelevant Media
Poster
Dissolution-Permeability Apparatus with Integrated In Situ Concentration Monitoring of both Donor and Receiver Compartments
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Novel HT Method for Parallel Excipient/Vehicle Formulation Studies
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Using Skin PAMPA For Transdermal Patch Testing
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In Situ Method for Monitoring Free Drug Concentration Released from Nanoparticles
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Degree and Extent of Supersaturation of Amorphous Pharmaceuticals and Their Flux through Lipophilic Membranes
Poster
Progress in pKa Determination Technology: Case Studies in Low and High Soluble Flavonoids
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Using flux experiments through artificial lipophilic membranes for predicting food effect for BCS Class 2 Compounds
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Application of simultaneous dissolution-absorption apparatus for screening formulations before bioequivalence studies
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Biorelevant drug release of Metformin dosage forms using complementary in vitro tools
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Differentiating itraconazole formulations based on the flux through artificial lipophilic membranes
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Utilization of pH-Metric Titration
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Application of Skin Pampa to Cosmetic Solvent Screening
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Application of MacroFLUX™ Apparatus for Screening Formulations before Bioequivalent Studies
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Supersaturation in additives and GI fluids
Poster
Determination of Polymer Effectiveness
Poster
In-situ Solubility Measurements of Ionizable Drugs
Poster
Determination of pKa values and Solubility pH Profiles of Selected ß blockers
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Validation of titrimetric measurement of pKa, logP and solubility
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Measuring the solubility of salts of basic drugs
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The intrinsic solubility of indomethacin
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A low volume method for screening Plasdone polymers
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Determination of Aqueous Solubility by Extrapolation
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Behavior of Basic Compounds in the Presence of Plasdone Polymers
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