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Investigating the driving force of membrane transport of carvedilol from supersaturated solutions achieved by ...

Investigating the driving force of membrane transport of carvedilol from supersaturated solutions achieved by ...

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When a poorly water-soluble active pharmaceutical ingredient (API) is formulated to enhance its dissolution, additives, such as surfactants, polymers and cyclodextrins have an effect not only on dissolution profile, but also on flux through the membrane. In order to fully understand these effects on flux, the driving force of membrane transport cannot be simplified to the total concentration gradient.
Investigating the driving force of membrane transport of carvedilol from supersaturated solutions achieved by ...

Poster

When a poorly water-soluble active pharmaceutical ingredient (API) is formulated to enhance its dissolution, additives, such as surfactants, polymers and cyclodextrins have an effect not only on dissolution profile, but also on flux through the membrane. In order to fully understand these effects on flux, the driving force of membrane transport cannot be simplified to the total concentration gradient.

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