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AAPS 2017 Supersaturation modelling poster KBox

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AAPS 2017 Supersaturation modelling poster KBox

Poster

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Pharmaceutical drug development pipelines continue to produce drugs with the challenge of poor aqueous solubility. We have ways to overcome the limitations.

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Dissolve Macro Orange

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AAPS 2017 Supersaturation modelling poster KBox

Poster

Purpose Pharmaceutical drug development pipelines continue to produce drugs with the challenge of poor aqueous solubility. Enabling formulation technologies, e.g., amorphous solid dispersions, are used to overcome such limitations via the creation of supersaturated states.

Poster

Dissolve Macro Orange
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Determination of the Intrinsic Dissolution Rate (IDR) from a Powder and using a Miniaturized Wood’s Apparatus
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Prediction of Caco-2 pH-Dependent Permeability based on High Quality in vitro Training Set
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Comparison of Miniaturized Intrinsic Dissolution Rate Measurement to Traditional Wood’s Apparatus
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Novel in vitro PK (non-animal PK) Assay for Excipient/Vehicle Formulation Studies
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Drug Permeation in Skin PAMPA and Franz Cell Model
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In Situ Solubility and Dissolution of Concentrated Solutions
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Powder Intrinsic Dissolution Rate Measurement: When is it Possible?
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Prediction of in situ Blood-Brain Barrier Permeability using BBB PAMPA Model
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Impact of Biorelevant Media on Apparent Solubility and Biopharmaceutical Classification of Poorly Soluble Compounds
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Nanoparticle Formulation of Gresiofulvin
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Evaluation of Optimized Caco-2 Permeability Measurements
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Supersaturation and Transmembrane Flux of Meloxicam
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Preparation, Physical Characterization and Solubility-Dissolution Testing of Loratidine Hot Melt Extrudates Prepared on a Laboratory Mixing Extruder
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Monitoring Supersaturation State of Solid Dispersions of Low Solubility Compounds
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Application of Skin PAMPA to Differentiate Between Topical Pharmaceutical Formulations of Ibuprofen
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Assessment of Transdermal Penetration Enhancement by Topical Pharmaceutical Excipients Using Skin PAMPA Method
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Universal Potentiometric Sensors: Application for Real Time Concentration Monitoring in Complex Biorelevant Media
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Real Time Monitoring of Dissolution, Supersaturation and Precipitation Processes in Dynamically Changing Biorelevant Media
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Novel HT Method for Parallel Excipient/Vehicle Formulation Studies
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