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Subcutaneously administered biopharmaceuticals

Subcutaneously administered biopharmaceuticals

Poster

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Scissor subcutaneous injection site simulator mimics the human body conditions to understand how formulation influences the behavior of a biotherapeutic in the subcutaneous injection site.
Subcutaneously administered biopharmaceuticals

Poster

Purpose A novel in vitro method for predicting how the characteristics of the subcutaneous tissue may influence the post-injection stability and diffusional properties of subcutaneously administered biopharmaceuticals has been developed. Scissor subcutaneous injection site simulator mimics the human body conditions and allows to understand how a formulation influences the behaviour of a biotherapeutic in the subcutaneous (SC) injection site. This allows to expedite the identification of lead formulations with optimal absorption properties following injection and facilitating rational formulation design.

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