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Dissolution Experiments in Lipid Layers

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Dissolution Experiments in Lipid Layers

Poster

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Dissolve Macro Orange

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Dissolution Experiments in Lipid Layers

Poster

Purpose To develop a method for studying the ability of polymers to prevent drug precipitation in dissolution experiments under changing (gastrointestinal) pH conditions and with a lipid phase to mimic absorption.

Poster

Dissolve Macro Orange
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Real time monitoring the extent of plasmid-liposome complexation using 2nd derivative fiber-optic UV spectroscopy
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Development and characterization of an in vitro method for investigating pharmacokinetic behavior of long-acting subcutaneously injected therapeutics
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Using NaOH and NaCl instead of KOH and KCl
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Introduction to log P and log D measurement using PionT3
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Measuring log P of samples that are hard to dissolve in water and octanol
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The Determination of Solubility - Pion CheqSol Explained
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The use of cosolvent pKa assays for poorly soluble compounds
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Measurement of Extreme pKas
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Scissor App Note_ECM-XR validation, peptides, mAbs, small molecules
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Development of Injectable PEGylated Liposome Encapsulating Disulfiram for Colorectal Cancer Treatment
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Nanoparticle Formation
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Surface dissolution imaging to investigate the influence of common ion effect on Papaverine hydrochloride
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Interplay between Ketoconazole Cocrystal Supersaturation and Trans-membrane Flux Behavior In Simulated Intestinal Fluids
Poster
Application of In Situ Potentiometric Sensors to Study Dissolution-Precipitation Behavior of Electrospray-Generated Loperamide Nanoparticles
Poster
Cyclodextrin-Based Orally Fast Dissolving Drug Delivery System of Aripiprazole and Its In Vitro Dissolution-Permeation Testing Using µFLUX
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Dissolution, Free Drug Concentration and Permeability of Crystalline Nanoparticle Formulation Study Using In Situ Fiber Optic and Potentiometric Techniques
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Real Time Dissolution Monitoring of Dual Component Drug Product Using Fiber Optic System
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MacroFLUX An Integration of Absorption Chamber with USP II Dissolution Apparatus
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Dissolution Rate and Apparent Solubility of Poorly Soluble Compounds in Biorelevant Fluids
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Universal Potentiometric Sensors Fast Determination of Free Ionized Drug Concentration in Micellar Solutions
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Universal Potentiometric Sensors: Application for Real Time Concentration Monitoring in Surfactant Containing
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Determination of the Intrinsic Dissolution Rate (IDR) from a Powder and using a Miniaturized Wood’s Apparatus
Poster
Penetration Enhancer Effect of Sucrose Esters
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Prediction of Caco-2 pH-Dependent Permeability based on High Quality in vitro Training Set
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Comparison of Miniaturized Intrinsic Dissolution Rate Measurement to Traditional Wood’s Apparatus
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Novel in vitro PK (non-animal PK) Assay for Excipient/Vehicle Formulation Studies
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Drug Permeation in Skin PAMPA and Franz Cell Model
Poster
In Situ Solubility and Dissolution of Concentrated Solutions
Poster
Powder Intrinsic Dissolution Rate Measurement: When is it Possible?
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Prediction of in situ Blood-Brain Barrier Permeability using BBB PAMPA Model
Poster
Impact of Biorelevant Media on Apparent Solubility and Biopharmaceutical Classification of Poorly Soluble Compounds
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Very Thin PAMPA Membranes Indicate Higher Antipyrene Permeability but are Fragile and Contain Leaky Water Pores
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Nanoparticle Formulation of Gresiofulvin
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In Vitro-In Vivo Correlation (IVIVC): Prediction of pK a at 37°C, From the Measured Value at 25°C
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Human Jejunal Permeability Predicted from Caco-2 Assay - A Biophysical Model Applied to Fluoroquinolone Antimicrobials
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Novel Device and Method for in situ UV Dissolution and Precipitation Monitoring in 96-well Plate
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Evaluation of Optimized Caco-2 Permeability Measurements
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Developing Skin PAMPA for Transdermal Patches
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Supersaturation and Transmembrane Flux of Meloxicam
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Universal Potentiometric Sensors Food Matrixes
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Preparation, Physical Characterization and Solubility-Dissolution Testing of Loratidine Hot Melt Extrudates Prepared on a Laboratory Mixing Extruder
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Evaluating Drug Salt Dissolution and Precipitation Processes for Rational Formulation Strategies
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Skin-PAMPA: A New Method for Fast Prediction of Skin Penetration
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Monitoring Supersaturation State of Solid Dispersions of Low Solubility Compounds
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Skin-PAMPA: Fast Prediction of Skin Penetration
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Comparison of Naproxen Release from Nano- and Microsuspensions with Its Dissolution from Untreated and Micronized Powder
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Soluplus® Maintains the Supersaturation of Carbamazepine from Amorphous Solid Dispersions
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In Situ Monitoring of Supersaturation State for Solid Dispersions of Low Soluble Compounds
Poster
Application of Skin PAMPA to Differentiate Between Topical Pharmaceutical Formulations of Ibuprofen
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Dissolution and Precipitation Monitoring of Crystalline Salts
Poster
Assessment of Transdermal Penetration Enhancement by Topical Pharmaceutical Excipients Using Skin PAMPA Method
Poster
Universal Potentiometric Sensors: Application for Real Time Concentration Monitoring in Complex Biorelevant Media
Poster
Real Time Monitoring of Dissolution, Supersaturation and Precipitation Processes in Dynamically Changing Biorelevant Media
Poster
Dissolution-Permeability Apparatus with Integrated In Situ Concentration Monitoring of both Donor and Receiver Compartments
Poster
Novel HT Method for Parallel Excipient/Vehicle Formulation Studies
Poster
Using Skin PAMPA For Transdermal Patch Testing
Poster
In Situ Method for Monitoring Free Drug Concentration Released from Nanoparticles
Poster
Degree and Extent of Supersaturation of Amorphous Pharmaceuticals and Their Flux through Lipophilic Membranes
Poster
Progress in pKa Determination Technology: Case Studies in Low and High Soluble Flavonoids
Poster
Using flux experiments through artificial lipophilic membranes for predicting food effect for BCS Class 2 Compounds
Poster
Application of simultaneous dissolution-absorption apparatus for screening formulations before bioequivalence studies
Poster
Using Integrated Absorption Chamber with USP II Dissolution Apparatus to Predict Risk of Drug-Drug Interaction from pH Modifying Agents: Poster
Poster
Biorelevant drug release of Metformin dosage forms using complementary in vitro tools
Poster
Differentiating itraconazole formulations based on the flux through artificial lipophilic membranes
Poster
Utilization of pH-Metric Titration
Poster
Application of Skin Pampa to Cosmetic Solvent Screening
Poster
Karl Box Sunrise Presentation
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Application of MacroFLUX™ Apparatus for Screening Formulations before Bioequivalent Studies
Poster
Supersaturation in additives and GI fluids
Poster
Determination of Polymer Effectiveness
Poster
In-situ Solubility Measurements of Ionizable Drugs
Poster
Determination of pKa values and Solubility pH Profiles of Selected ß blockers
Poster
Validation of titrimetric measurement of pKa, logP and solubility
Poster
Measuring the solubility of salts of basic drugs
Poster
The intrinsic solubility of indomethacin
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A low volume method for screening Plasdone polymers
Poster
Determination of Aqueous Solubility by Extrapolation
Poster
Behavior of Basic Compounds in the Presence of Plasdone Polymers
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