resources

A novel in vitro method to model the fate of subcutaneously administered biopharmaceuticals and associated formulation components

A novel in vitro method to model the fate of subcutaneously administered biopharmaceuticals and associated formulation components

Publication

This content has been restricted to logged in users only.

Create an account to view resources.

A novel in vitro method to model the fate of subcutaneously administered biopharmaceuticals and associated formulation components

Publication

Subcutaneous (SC) injection is becoming a more common route for the administration of biopharmaceuticals. Currently, there is no reliable in vitro method that can be used to anticipate the in vivo performance of a biopharmaceutical formulation intended for SC injection. Nor is there an animal model that can predict in vivo outcomes such as bioavailability in humans. We address this unmet need by the development of a novel in vitro system, termed Scissor (Subcutaneous Injection Site Simulator)

Previous post