The Homogenization Process: How BEE Makes It Better

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David Shechter
Jan 19, 2017
min read
The Homogenization Process: How BEE Makes It Better

Homogenization, also known as micronization or particle size reduction, is a common (and increasingly growing!) technique among many industries, including pharmaceutical, biotech, cosmetic, and food. The benefits of homogenization are endless. Homogenization increases shelf life and stability of products, results in better taste, look, and texture of food items, and in many cases, it offers a cost savings as well -- smaller particles are more evenly distributed throughout any desired medium, allowing for less of the often expensive active ingredients to be used.

Before choosing the right homogenizer for the task at hand, it is important to understand the desired application. Pion's BEE brand offers a variety of high pressure homogenizers that are suitable for virtually all applications – from small laboratory and R&D settings up to pilot plants and 24/7 manufacturing. Continue reading to learn more about the high pressure homogenizers, and how our homogenizers can make the homogenization process faster, easier, and more effective.  

Laboratory Homogenizers

Pion's BEE brand offers several laboratory homogenizers, suitable for the creation of emulsions and dispersions, as well as work with cell rupture and liposomes. Our laboratory homogenizers include the Nano DeBEE, Micro DeBEE, and Mini DeBEE models. These high pressure homogenizers are suitable for a variety of applications, including new product development, product improvement, and experimentation and scale-up studies. Our laboratory homogenizers also offer the following benefits and features:

  • Maximum operating pressure of up to 45,000 psi
  • Maximum capacity of up to 400 mL/min and 22 L/hr
  • Suitable for sanitary applications
  • CE and cGMP compliant
  • Minimum sample size as low as 5ml
  • Easy cleaning and maintenance with no disassembly required

Pilot and Industrial Homogenizers

While our high pressure laboratory homogenizers are best for small-scale testing and experimentation, our pilot and industrial homogenizers are well-suited for larger operations. Our pilot and industrial homogenizers include the DeBEE 2000, and DeBEE 4000, and are equipped with our own patented Emulsifying Cell (EC) technology, which offers a linear process which enables us to guarantee the scalability of results. Additional benefits and features include:

  • Constant pressure with electronic synchronization
  • Numerous cylinder sizes available
  • Unique Clean In Place (CIP) position
  • Password protected operation
  • Industrial tower light with buzzer
  • Menu guided maintenance and calibration

To learn more about our suite of high pressure homogenization equipment, as well as how our products can best suit your needs, please contact us today.

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