How to Select Your Perfect Laboratory Homogenizers

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David Shechter
Oct 29, 2015
min read
How to Select Your Perfect Laboratory Homogenizers

Are you a researcher in the pharmaceutical, biotech, chemical, food, or beverage industry? If you answered yes to any of these you are likely familiar with laboratory homogenizers. But familiarity doesn’t necessarily translate into widespread knowledge of the market. When looking to select a homogenizer for your laboratory, it is critical to select a model that accommodates the required applications, and which will serve long-term use. Keep reading for a breakdown of factors to consider as you begin your search.

Various laboratory homogenizers exist on the market, and selecting the type that’s right for you should be step 1 in your buyer’s journey. Although all laboratory homogenizers can accomplish emulsions, cell disruptions and more, each functions optimally for distinct applications.

  1. Ultrasonic Homogenizer -- Best for samples that are incredibly difficult to disrupt, such as tough animal tissues, spores, soil samples, and liposomes. (1)
  2. Mechanical Homogenizer - The tearing & cutting accomplished by mechanical shearing is well-suited for samples that need this type of treatment; these include animal tissues and cells.
  3. Pressure Homogenizer - One of the most efficient fluid processing systems for cell disruption and particle size reduction, particularly for applications that require minimum particle sizes and homogenous mixtures.

Now that you have selected your homogenizer type, it is time to analyze specific factors that will help you choose a brand and specific model. The best way to use this information is to determine which factors are important to you. For those deemed as important, the next step will be determining what performance level you require from each.

  1. Maximum operating pressure. Some models can achieve operating pressures of up to 45,000 PSI.
  2. Mixing speed. Higher mixing speeds will be particularly important for difficult-to-disrupt samples.
  3. Processing setup. Parallel, reverse, and dual feed are three of the more common setups. Some machines allow the user access to all, depending on the application.
  4. Processing range. How much volume do you need processed at a time? Some homogenizers are tailored to small samples, while others, particularly industrial homogenizers, target larger volumes.

Pion: High Pressure Homogenizers Worth Selecting

Have you decided that a pressure homogenizer will be the right choice for you? Begin your search with Pion's BEE brand laboratory homogenizer. Pion is trusted by pharmaceutical researchers and lab managers around the world. We deliver an array of key benefits, such as production of cell lysates, nano/micro emulsions and dispersions and lipids and suspensions. Our homogenizer processes can be controlled to better suit your product; for example, pressure can be adjusted to be gentler or harsher and the results can be scaled to manufacturing. Finally, our equipment is easy to use, produces higher yield in less time, and results are reproducible and scalable.

Pion offers a variety of laboratory models that can help you achieve high quality applications. Learn more about Pion and our laboratory homogenizers here.

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