The Benefits of a Laboratory Homogenizer For Cell Lysis

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David Shechter
Jan 7, 2016
min read
The Benefits of a Laboratory Homogenizer For Cell Lysis

Are you a scientist of the pharmaceutical or biotechnology industry? No matter which category you fall under, your life will be far improved when a laboratory homogenizer is a part of it. Laboratory homogenizers are commonly used to obtain intracellular contents or for biochemical analysis.

Equipment Flexibility

  • Accommodates for multiple cell types

Gaining access to intracellular contents or conducting biochemical analysis requires penetration of the protective cell barrier. In bacterial, plant, and yeast/fungal cells, this means using enough force to penetrate the tough cell wall. Yet mammalian cells require a gentle method that will break through the cell membrane but not exert so much force so as to destroy the intracellular material. Laboratory homogenizers can achieve both the high and gentle forces needed for a variety of cell types.

  • Adjusts for sample size

Although this point will be touched on below in the Scalability for Manufacturing section, it is also relevant to flexibility in process. Laboratory homogenizers are flexible in that they can be customized for both small and large sample sizes. This key factor has the potential to save researchers valuable time and money.

  • Customizable forces

High-quality laboratory homogenizers offer the option to adjust mechanical forces. This option allows the user to achieve a better result by customizing the equipment to a specific product. Examples of these customizable forces include process intensity, turbulence, shear, and cavitation.

Scalability for Manufacturing

A scalable system/method is one that has the ability to adapt to increased demand. This point is particularly significant for researchers involved in the pharmaceutical industry or any work that may move from small-scale experimentation to large-scale manufacturing. Before you start any small-scale project, determine if you foresee it going into manufacturing. If that answer is ‘yes’, it will be advisable to obtain a laboratory homogenizer from a reliable company that also offers pilot-plant and industrial machines. By doing so, you will save both time and money, the two factors most at play when it comes to scalability.

Pion Inc.: The BEE Brand Homogenizer Advantage

Are you in need of equipment to support your cell lysis technique? BEE homogenizer technology is trusted by researchers and lab managers around the world. Pion delivers an array of key benefits, such as production of nano/micro emulsions and dispersions and lipids and suspensions; these can be used for applications such as injectables, targeted drug delivery, inhalants, time release, anesthetics, and importantly, vaccinations.

In addition, we have extensive experience in the challenges that our customers face as they transition from concept, through to R&D, clinical trials, all-important FDA approval and finally, to manufacturing.

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