How the Nano DeBEE Can Benefit Laboratory Applications

Pion Favicon
Tal Shechter
Jun 16, 2016
min read
How the Nano DeBEE Can Benefit Laboratory Applications

Mixing equipment, from the simple blender to the complex homogenizer, is a key component of the daily lab research that leads to innovative products. While homogenizers are one of the more popular mechanical mixers, the numerous models and options can leave a potential user in a tizzy. Here we will analyze the Nano DeBEE, one such homogenizer model, for how it can benefit laboratory applications, and why it may be a better selection than other models.

Proprietary Emulsifying Cell

The Emulsifying Cell, unique to Pion's BEE brand homogenizers, is designed to replicate passing through the cell multiple times. This works when absorption is induced by the Cell’s reactors to reduce particles over again as they exit, thus having the effect of multiple passes with the cost and time efficiency of only one or two passes. Additionally, it provides the user with the option of higher shear (compared with other high shear mixers) and gives the user flexibility to alter the process, thus widening its versatility.

Multiple Homogenizing Forces

The Nano DeBEE is unique in that, while most other mixing equipment imparts 1-2 forces, it can impart multiple forces in a single instrument. Firstly, turbulent flow can vigorously premix a product before passing through the nozzle. Next, cavitation occurs from a large pressure drop as the sample exits the nozzle. Thirdly, within the proprietary Emulsifying Cell (indicated above), the product creates a strong physical force upon impact at the Cell’s end fixture. And finally, the shear forces present through the entirety of the Emulsifying Cell allow for completion of a process that would otherwise require more time and resources.


Although the above points about multiple forces may sound appealing, what if you require a sensitive process that will not destroy critical intracellular molecules? BEE has it covered by allowing the user to customize process operation for product optimization. For example, the amount of force (cavitation, impact, shear) a sample is exposed to can be adjusted; additionally, process duration, pressure, and flow are user-controlled, allowing for a unique level of autonomy in technique. (1)

Range of Sample Volumes

While some laboratory applications require small sample sizes of 15 mL or below, others may be using 200 mL and above. While some mixing equipment is designed to handle either small or large samples, but not both, the Nano DeBEE can process a wide range of sizes, allowing for more diverse use. This is particularly useful for applications that may require scaling.

Pion: The Homogenizer Advantage

On determining which homogenizer will be right for your lab, begin your search with Pion's BEE brand technology. We are globally recognized among laboratory managers and researchers for our high quality products and excellent customer support. Cell lysis and particle size reduction are two of a variety of applications for Pion's BEE brand homogenizers; nano/micro emulsions, lipids, suspensions, and dispersions are also easily achievable. Additionally, the homogenizer processes can be controlled to suit your product, which will allow you to customize to your cell type. And finally, the equipment is easy to use, produces higher yield in less time, and achieves results that are reproducible and scalable.

Learn more about how Pion's BEE brand homogenizers can improve your experimentation by contacting us today.

Prev Blog
Next Blog