oral formulation

Oral Formulation Delivery

Get insights earlier for oral formulation development: optimize formulations to be administered orally & absorbed through the stomach, intestine, or GI tract.

Predicting Dose–Exposure-Response During Oral Formulation DevelopmentPredicting Dose–Exposure-Response During Oral Formulation Development
Oral Formulation

Predicting Dose–Exposure-Response During Oral Formulation Development

oral formulation

Optimal dose selection identifies the formulation that best balances the benefit of the drug with risk

Optimal dose selection identifies the formulation that best balances the benefit of the drug with risk
Characterization of physicochemical properties is one of the key challenges to develop a pharmaceutical active ingredient into a drug.

Dissolution
The measure of a drug dissolving

Ionization
The measure of dissociation into ions which occurs when an electrolyte is dissolved

Absorption
The measure of absorption of the formulation

Solubility
The measure of the maximum concentration of a solute that can dissolve in a solvent at a given temperature

Permeability and Flux
The measure of the ability to cross membranes

Lipophilicity
The measure of the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents

oral formulation

Pion’s instruments provide a range of PK/PD measurements:

  • Solubility
    The measure of the maximum concentration of a solute that can dissolve in a solvent at a given temperature
  • Permeability and Flux
    The measure of the ability to cross membranes
  • Lipophilicity
    The measure of the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents

Oral Formulation Delivery

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