Blog Posts to Explore

Blog

June 24, 2024

Developing poorly water-soluble drugs

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Poorly water-soluble drug development

Blog

June 18, 2024

Pion Predictor Software

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Pion Predictor Software for Drug Development

Blog

June 13, 2024

What are PROTACs?

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What are PROTACs Proteolysis targeting chimeras

Blog

May 30, 2024

Subcutaneous injection basics and formulation screening during drug development

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Drug development subcutaneous injection formulation screening

Blog

May 16, 2024

What is intrinsic dissolution rate?

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Intrinsic dissolution rate definition

Blog

May 2, 2024

Formulating with Less API: Exploring the Application of API Sparing Techniques in Oral Drug Development

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API Sparing Techniques in Oral Drug Development

Blog

April 24, 2024

What are solubility and supersaturation?

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Solubility and supersaturation

Blog

April 9, 2024

What is the difference between drug discovery, drug development and drug formulation?

drug development

Content Uniformity

Dissolution testing

Drug permeability

Injectables formulation

Drug discovery drug development and drug formulation

Blog

April 2, 2024

The Basics of Drug Flux and Permeability

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In vitro flux measurements predict in vivo drug permeability

Blog

March 26, 2024

Crossing the Blood Brain Barrier

PAMPA

oral drug development

Blood brain barrier

Pion PAMPA measures permeability of a compound across an artificial membrane that mimics the properties of the BBB

Blog

March 19, 2024

How Are Poorly Soluble Compounds Formulated into Drugs?

drug development

log P

oral solid dose

physchem characterization

pKa

How poorly soluble compounds are formulated into drugs

Blog

March 13, 2024

Speeding Sample Preparation and API Extraction from Solid Oral Dosage Formulations for QC Content Uniformity testing

Dissolution testing

oral solid dose

oral drug development

PrepEngine

PrepEngine speeds sample prep and API extraction from oral solid dose formulations

Blog

March 12, 2024

Particle Size Reduction 101: Homogenization, Dispersions & Emulsions

Dispersions

Emulsions

Homogenization

Particle Size Reduction

Particle size reduction is the process of reducing particle size using techniques, like homogenization, to create dispersions & emulsions.

Blog

March 11, 2024

In Vitro Surface Dissolution Imaging Assists in the Development of Intestine and Colon Delivered Drugs

Dissolution testing

drug development

oral drug development

Pion's SDI2 Surface Dissolution Imaging instrument for drug development

Blog

March 5, 2024

Rethinking Drug Formulation: The Motivation Behind Embracing Subcutaneous Delivery

drug development

Injectables formulation

Subcutaneous delivery

The re-formulation of drugs for subcutaneous delivery represents a transformative trend in the pharmaceutical industry

Blog

March 1, 2024

What is the Pion PrepEngine?

Cannabis

Cell Disruption

Dissolution testing

Content Uniformity

Pion PrepEngine multi-station lab blending instrument for content uniformity dissolution cannabis testing

Blog

February 27, 2024

What is Pion's MacroFLUX and How is it Related to Membrane Permeability?

Dissolution testing

drug development

oral drug development

oral solid dose

Drug permeability

MacroFLUX is a valuable asset for drug product optimization, batch-to-batch comparability and bioequivalence testing

Blog

February 27, 2024

How the Cell Wall Effects Homogenization

Cell Walls

Homogenization

Learn exactly how the cell wall effects homogenization so that you have all of the knowledge you need to be successful with your applications.

Blog

February 20, 2024

Exploring Protein Conformation and Stability in the Subcutaneous Space

drug development

Injectables formulation

The SCISSOR offers a unique opportunity for early screening of the in vivo performance of subcutaneously administered therapeutics in preclinical evaluation.

Blog

February 13, 2024

Why Do We Care About Protein Aggregation Post-Subcutaneous Injection?

Biotechnology

Pharmaceutical

By understanding the potential causes of aggregation and its consequences, researchers can minimize the risk of immune responses and inflammation

Blog

February 9, 2024

Real-time In situ/In vitro Dissolution Measurements in Drug Development and Their Connection to Particle Size: The link between homogenization/micronization and dissolution

Dissolution testing

drug development

In situ Dissolution Measurements and Biorelevant Solubility and Dissolution of Poorly Soluble Drugs

Blog

February 6, 2024

The Advantages of BEE brand homogenizers for cell lysis

Cell Disruption

Cell Lysis

drug development

High Pressure Homogenization

Pion's BEE brand homogenizers for cell lysis

Blog

January 30, 2024

Parallel artificial membrane permeability assay (PAMPA) and its role in drug development

drug development

oral solid dose

Pharmaceutical

PAMPA

Parallel artificial membrane permeability assay (PAMPA) BBB GIT kits

Blog

January 25, 2024

Advantages of fiber-optic probe-based UV spectrometers

Dissolution testing

Fiber optic UV spectrometers in dissolution testing offer improved sensitivity, real-time monitoring, and compatibility with different dissolution methods.

Pion Blog

Developing poorly water-soluble drugs

Pion Predictor Software

What are PROTACs?

Subcutaneous injection basics and formulation screening during drug development

What is intrinsic dissolution rate?

Formulating with Less API: Exploring the Application of API Sparing Techniques in Oral Drug Development

What are solubility and supersaturation?

What is the difference between drug discovery, drug development and drug formulation?

The Basics of Drug Flux and Permeability

Crossing the Blood Brain Barrier

How Are Poorly Soluble Compounds Formulated into Drugs?

Speeding Sample Preparation and API Extraction from Solid Oral Dosage Formulations for QC Content Uniformity testing

Particle Size Reduction 101: Homogenization, Dispersions & Emulsions

In Vitro Surface Dissolution Imaging Assists in the Development of Intestine and Colon Delivered Drugs

Rethinking Drug Formulation: The Motivation Behind Embracing Subcutaneous Delivery

What is the Pion PrepEngine?

What is Pion's MacroFLUX and How is it Related to Membrane Permeability?

How the Cell Wall Effects Homogenization

Exploring Protein Conformation and Stability in the Subcutaneous Space

Why Do We Care About Protein Aggregation Post-Subcutaneous Injection?

Real-time In situ/In vitro Dissolution Measurements in Drug Development and Their Connection to Particle Size: The link between homogenization/micronization and dissolution

The Advantages of BEE brand homogenizers for cell lysis

Parallel artificial membrane permeability assay (PAMPA) and its role in drug development

Advantages of fiber-optic probe-based UV spectrometers

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