Indigo™ and IndigoSAM™ represent the latest software innovation fort the Rainbow Dynamic Dissolution Monitor® System. Combining UV with the technology built into the Rainbow, these software platforms give formulation and dvelopment chemists the ultimate in flexibility for in situ dissolution analysis.
Indigo™
This is a flexible software tool for the Rainbow for use in the R&D and formulation laboratory. The Indigo™ user interface is simple and intuitive to navigate because it uses one screen interface to handle all tasks. Simply clicking tabs on the Indigo™ desktop takes the user from activity to activity with full access to every step at any time. Setting up a dissolution experiment or UV measurements is straightforward. No longer will it take more time to setup than to run the experiment.
IndigoSAM™
This secure account manager has a full suite of security tools to Indigo for GMP and QC environments.* These include digital signatures, data audit trails and more. IndigoSAM™ provides Indigo users with a full suite of security tools commonly used in GMP and QC environments. Methods developed in Indigo™ may be imported, locked down, and run in the secure environment of IndigoSAM™. Four levels of user access and security are provided for user-creation and control, data audit, method creation and experimentation.
Customizable Data Sampling Rates
Indigo™ allows you to customize the sample rate of your experiment. In seven steps, the sample rate can be adjusted to suit the dissolution rate. Collecting more data on the steep parts and less on the flat regions, reduces the amount of unnecessary data.
Complete Data Collection
Using the Rainbow’s built in photodiode array, Indigo™ collects data throughout the wavelength range. This provides far richer data sets than those obtained by single or multiple wavelength spectrometers. On the fly, calibrated conversion of absorption vs. photodiode number to absorption vs. wavelength in 2 nm steps ensures that data files are kept as small as possible. Because full spectra data sets are saved, data analysis can be performed in different ways after data collection. The multithreaded design of Indigo allows viewing and changing data sets already saved in parallel during data collection.
Data Processing
Indigo™ features both baseline subtraction and 2nd derivative correction for sloping baselines of especially turbid solutions. In case of 2nd derivative spectra, Indigo allows the selection of different levels of curve smoothing. Both single wavelength and Area Under the Curve (AUC) may be used in calculation of % dissolved using either single wavelength, wavelength range, or full range spectra. Spectra for standards are saved and can be made available to more than one dissolution run, further saving time and effort.
*GMP and 21 CFR 11 compliance in any given IT environment is the sole responsibility of the user.
